Assessment, risk factors and recommendations

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Breast cancer occurs when breast cells begin to grow and divide uncontrollably. Aside from some types of skin cancer, it is the most common cancer in women in the United States.

According to American Cancer Society (ACS), the average lifetime risk of a woman of developing breast cancer is about 13%. This translates to a 1 in 8 chance of developing breast cancer.

However, for some, the risk of breast cancer is increased. These people are said to have a high risk of breast cancer.

Find out what it means to be at high risk for breast cancer, what factors put you at high risk, and recommendations for early detection of cancer in people at high risk.

There is currently no standardized approach to assess a person’s risk of breast cancer. However, there are several tools that help doctors identify people at high risk for breast cancer.

Breast cancer risk assessment tools are heavily based on your personal and family history. However, they also take other factors into account. Here are some examples of commonly used tools:

  • Breast Cancer Risk Assessment Tool (BCRAT), also known as the Gail Model
  • International Breast Cancer Intervention Study (IBIS) risk calculator, also known as the Tyrer-Cuzick model
  • Claus model, based on the study of cancer and steroid hormones

Risk assessment tools provide a variety of metrics. These can include 5-year risk, 10-year risk, and lifetime risk.

What is considered high risk may vary by location. In the United States, people with an estimated 5-year risk of 1.67 percent or more are generally considered high risk.

Doctors consider several factors to determine if you are at high risk for breast cancer. All of these factors, except pregnancy history and radiation exposure, are things you cannot change:

  • Family history: If you have had one or more close relatives, such as parents, siblings or children with breast cancer, your risk increases.
  • Genetic: Having inherited genetic mutations that are associated with familial cancer syndromes, especially those BRCA1 Where BRCA2, greatly increases your risk of developing breast cancer.
  • Age: The risk of breast cancer increases with age.
  • Personal story: A personal history of certain breast conditions increases your risk for breast cancer. These include:
  • Menstrual history and pregnancy: Starting your period at an early age, going through menopause later, or not having children are all associated with an increased risk of breast cancer.
  • Breast density: Having dense breasts having a mammogram increases your risk of breast cancer.
  • Radiation exposure: If you have received radiotherapy between the ages of 10 and 30, your risk of breast cancer is higher.

Remember that there is no standardized method for determining the risk of breast cancer. While breast cancer risk assessment tools are important in helping to estimate risk, they usually do not consider all of the above factors.

For example, the BCRAT tool requests information on age, family history of breast cancer, and menstrual and pregnancy history. However, it does not use information about genetics, personal history of breast conditions, or radiation exposure.

For this reason, in addition to the results of one or more risk assessment tools, your doctor will also assess other details of your personal history, family history, and lifestyle to better assess your risk. breast cancer.

People at high risk of breast cancer may benefit from additional monitoring or screening. It can help detect and start treatment for breast cancer at an early stage.

Doctors may also stagger screening tests from 6 months to increase monitoring to twice a year, rather than once a year. For example, they may recommend a mammogram in January and an MRI in June.

Currently the ACS recommends that the following people have both mammography and breast MRI each year, often starting at age 30:

  • those with a lifetime risk of breast cancer of 20 to 25 percent or more according to risk assessment tools
  • people with a known mutation in BRCA1 Where BRCA2 or those who have a close relative with a BRCA1 Where BRCA2 mutation
  • people who have received radiation therapy to their chest between the ages of 10 and 30
  • those with a personal or family history of the following familial cancer syndromes:
    • Bannayan-Riley-Ruvalcaba syndrome

There are advantages to using both types of screening technology. Although a Breast MRI is more likely to find cancer, it may miss changes than a mammogram would detect.

In addition, the ACS states that there is currently not enough evidence to recommend an annual breast MRI for people with dense breasts or a history of breast conditions like DCIS, LCIS, ADH and ALH.

If this applies to you, ask your doctor when to start screening for breast cancer and whether or not a breast MRI should be included. They can take your other risk factors into account to determine the best course of action.

People at high risk of breast cancer have an increased risk of developing breast cancer compared to a person at medium risk. There are various risk assessment tools that can help estimate breast cancer risk.

Some of the most important factors in determining whether a person is at high risk for breast cancer are family history and genetics. Other factors, such as age, a history of certain breast conditions, and breast density also play a role.

People at high risk for breast cancer may benefit from annual mammograms and breast MRI scans to help detect breast cancer at an early stage. If you are concerned that you may be at high risk for breast cancer, be sure to discuss this with your doctor.

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Sources

1/ https://Google.com/

2/ https://www.healthline.com/health/breast-cancer/high-risk-breast-cancer

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