Group of radiologists push for ‘assessment’ of breast cancer risk before age 25

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By Cara Murez HealthDay Reporter

(Health Day)

This first step is especially important for black or Ashkenazi Jewish women, the guideline authors said.

Women who are at higher risk due to their genes, such as those who carry the BRCA1 gene mutation, as well as women exposed to chest radiation therapy at a young age and those whose risk of breast cancer at life is 20% or more should start undergoing an MRI. screening began between ages 25 and 30, the American College of Radiology (ACR) now recommends. These women should start having annual mammograms between the ages of 25 and 40, depending on their specific risk.

“These evidence-based updates should spur more informed doctor-patient conversations and help providers save more lives,” she said in an ACR press release.

The ACR also recommended that women who were diagnosed with breast cancer before age 50 and those with a personal history of breast cancer and dense breasts have an additional breast MRI every year. Those who cannot have an MRI should have contrast-enhanced mammography (CEM) instead.

For women at average risk, the ACR recommends continuing annual screening beginning at age 40.

The breast cancer death rate in the United States has dropped 43% since mammography became widespread in the 1980s, according to data from the US National Cancer Institute Surveillance, Epidemiology, and End Results (SEER). The rate had not changed in the previous 50 years. Breast cancer rates, meanwhile, have not changed for men, who undergo the same treatment as women but without regular screening.

Reasons for black and other minority women to get screened earlier include the fact that before the age of 50, minority women are 127% more likely to die of breast cancer than white women. They are also 72% more likely to be diagnosed with breast cancer and 58% more likely to be diagnosed with advanced breast cancer.

Even with roughly equal incidence rates, black women are still 42% more likely to die from breast cancer, less likely to be diagnosed at stage 1 but still twice as likely to die from a early breast cancer.

Black women also have a twice as high risk of aggressive breast tumors – “triple negatives” – and a higher risk of BRCA1 and BRCA2 genetic mutations.

“Since 1990, breast cancer death rates among black women, who develop and die earlier from the disease, have declined only about half as fast as among white women,” the co said. – author of the guidelines. Dr. Stamatia DestounisChairman of the American College of Radiology Breast Imaging Commission and Managing Partner at Elizabeth Wende Breast Care in Rochester, NY

“We continue to regularly review the latest evidence and update our recommendations to help save more black women and other high-risk people from this deadly disease,” Destounis said in the statement.

SOURCE: American College of Radiology, press release, May 3, 2023

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