[ad_1]
A craving for sugar has always been attributed to an imbalance in blood sugar levels in your body. If you crave sugary foods every time you eat your meal, you have serious health problems. In a recent study by a team of IIT researchers, Mandi, the insidious link between excess sugar and concomitant fatty liver disease, known as non-alcoholic fatty liver disease (NAFLD) in medical jargon, found been unveiled.
The team identified the molecular link between the buildup of sugar and fat in the liver and alerted the public to the dangers of it. It is now up to us to reduce sugar intake to stop NAFLD in its early stages.
Let’s get down to business and think about what NAFLD is and what causes it:
Non-alcoholic fatty liver disease (NAFLD)
Simply put, NAFLD refers to a medical condition characterized by an accumulation of excess fat in the liver. The disease is so insidious that people under the influence of it are not aware of having it because the symptoms do not appear between the early and middle stages. The build-up of excess fat can irritate liver cells and, if left untreated, can lead to scarring of the liver (cirrhosis) and long-term cancer.
What are the causes of NAFLD
Overconsumption of sugar – both table sugar (sucrose) and other forms of carbohydrates – is undoubtedly one of the many reasons that cause NAFLD. Consuming excess sugar and carbohydrates causes the liver to convert them to fat through a process called De Novo hepatic lipogenesis, or DNL, said Dr. Prosenjit Mondal, Associate Professor, School of Basic Sciences, IIT Mandi.
According to the research team, the molecular link between the accumulation of sugar and fat in the liver would go a long way in developing treatments for the disease.
What the study found
The results – published in the Journal of Biological Chemistry – indicate that the hepatic NF-KB p65 sugar-mediated shuttle reduces levels of another protein, witch, which in turn biochemically activates DNL in the liver. cascading, Mondal was also cited.
Read all Latest news, latest news and Coronavirus news here
.
[ad_2]
Pictures Credit