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Intelligence has previously been linked to the high quality of sperm, an idea that will now be confirmed as scientists have found that the brain and male testes have many similarities.
A group of scientists, led by the University of Aveiro in Portugal, compared the proteins of 33 types of tissues and found that the testes and the brain contain more than 13,000 proteins, many of which are concerned with improving the tissues and cellular communication.
The investigation also revealed similarities between human neurons and sperm, as they each undergo exocytosis: Neurons use this process to pass to each other, and sperm use it when they fuse with an egg.
Exocytosis is the method by which materials inside a cell move to an outside atmosphere.
“This is an under-explored subject, and the link between these tissues needs to be clarified, which can help capture dysfunctions affecting the brain and testes. [singular], in addition to developing improved therapeutic methods, ”shared the researchers in the study, published in the journal Royal society.
The human brain is essentially the most complex and distinctive organ in the body, but a new study has identified another with similar characteristics – the male testis. A group of scientists have found that men’s brains and testes have many mobile and molecular similarities
The analysis was carried out by scientists from Portugal and the United Kingdom, who embarked on their work evaluating completely different tissues, including the brain, testes, coronary heart, cervix and placenta.
“Of the 14,315 and 15,687 proteins that represent the human brain and the testis proteome, respectively, 13,442 are prevalent in every tissue,” the group wrote in the study.
The majority of proteins are concerned with exocytosis, tissue enhancement and cellular communication, which the group was not surprised to learn given the similar abilities of the two tissues.
The brain and testes require enormous amounts of energy for the main tasks – to collect and produce a certain number of millions of sperm per day, Scientific alert stories.
The investigation also found similarities between human neurons and sperm, as they each undergo exocytosis: Neurons use this process to pass neurotransmitters to each other, and sperm use it to fuse with an egg.
“Of the 14,315 and 15,687 proteins that represent the human brain and testicular proteome, respectively, 13,442 are prevalent in every tissue,” the group wrote in the study.
For this reason, every tissue is subject to oxidative stress which could damage cells and tissues.
To combat this drawback, both have their own protective barrier: a blood-brain barrier and a blood-testicular barrier.
One of the findings was one of the most prevalent proteins that undergo exocytosis in the brain.
When exocytosis occurs in the brain, cells pass neurotransmitters to each other and this is a key process throughout fertilization.
Exocytosis triggers the development of neurons, allowing them to develop branch-like arms and for sperm, the method helps to fuse with an egg.
Taking a closer look at the two tissues, the group concluded that neurons in the brain and sperm in the testes have similar characteristics.
The group finally recognized 5,048 proteins widespread in human neurons and sperm
“Several varieties of ‘neuronal’ receptors, such as the receptors for glutamate and gammaaminobutyric acid (GABAA), glycine and nicotinic acetylcholine, have been found in semen,” according to the study.
“Also in semen, ‘neural’ receptors play a very important role in its regular functioning, as well as in the acrosome response, capacitation and motility of sperm. “
The group eventually recognized 5,048 proteins widespread in human neurons and sperm.
“The human neuron and the sperm are very distinct cells; nonetheless, they share a number of molecular options and a huge variety of proteins are prevalent in every cell, primarily those concerned with exocytotic and cellular signaling processes, tissue enhancement, and brain / neuron associated processes. Adds the study.
“Understanding these similarities and their implications has become a matter of curiosity among the many scientists in the vicinity. Indeed, an affiliation of intelligence with certain high-quality parameters of semen has been reported and a relationship between dysfunctions of the human brain and testes has further been evident.
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